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DOI: 10.1016/j.yfrne.2012.07.001 [DOI] [PubMed] [Google Scholar] 80.Seyedi M, Gholami F, Samadi M, Djalali M, Effatpanah M, Yekaninejad MS, et al

Additionally, lactoferrinan iron-binding glycoproteinreduces NF-B (p65) and TNF- levels, lessening inflammation and depressive behaviors in rats subjected to chronic restraint stress

While in humans this region is only ~10% of the area, in rodents which are mainly used for IN administration studies, the olfactory region can make up to 50% of the total area [6, 14, 15]

For example, reduced GPX enzyme activity increases the need for selenium