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Consequently, any change in either of these network players influences the regulatory network (Szarka et al., 2013)
doi: 10.1111/j.1365-2958.2009.06750.x

Pathways associated with mitochondrial biogenesis, and activated in response to energy deficit, include the activation of the peroxisome PGC-1 axis, activation of the AMP-activated protein kinase (AMPK), and Sirtuin 1 activation [63]

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