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There are several reasons why you might consider this treatment

Since mouse microbiome profiles often highly correlate with body weight and fat composition, this study was designed to test whether the cecal microbiomes of DIO mice treated with NNMTi and LD were comparable to the microbiomes of age-matched lean counterparts and distinct from microbiomes of DIO mice maintained on a high-fat Western diet (WD) or subjected to LD switch alone

But for most people, the effect is more of a gradual return to your normal baseline, not a sudden, dramatic spike in energy

Studies in aging-prone and cancer-prone rodent models highlight its relevance in the fields of gerontology and cancer biology 1,3,4

Altered Methylation: Preserved SAM for other methylation reactions 5