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Moreover, evidence from an increasing number of research studies suggests that, in addition to its effects on neuroendocrine and metabolic functions, GHSR contributes to the regulation of the mesocorticolimbic pathway and influences diverse reward-related behaviors in response to various stimuli through both ligand-dependent and -independent mechanisms (49)

Additionally, its protective effects on mitochondrial function further bolster neuronal energy metabolism and enhance resilience against damage precipitated by stress

[PubMed] [Google Scholar] 127.Edelman M.J., Bauer K., Khanwani S., Tait N., Trepel J., Karp J., Nemieboka N., Chung E.-J., Van Echo D

doi: 10.1016/j.neuint.2012.06.013