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Conditional deletion of the p85 gene in skeletal muscle and heart showed normal growth [68], but when these mice were crossed with p85 null mice, the resulting double-mutant animals showed reduced heart but not reduced skeletal muscle size [68]
10.1371/journal.pone.0026915 6
It enhanced the function of the neurotransmitter acetylcholine via muscarinic receptors [76], and affected N-methyl-D-aspartate receptors in rat models in vivo, increasing cell membrane permeability [77]
In 2023, they found similar nanoparticles in the kidney cells of humans with normal renal function, likely from contrast agents
Cancer Discov 11, 26022619 (2021)
