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For initial analysis of glucose-related metabolism we cultured virus-specific T cells ex vivo in the presence of the fluorescent glucose-analogue 2-NBDG, which serves as a surrogate for glucose uptake (22)

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When symptoms are attributed to high B12 intake, they typically include: Skin reactions : Acne-like eruptions or rosacea-type rashes, particularly with hydroxocobalamin injections (listed as rare adverse effects in the product information) Gastrointestinal disturbances : Mild nausea, diarrhoea, or abdominal discomfort Headaches : Occasional reports of headache following B12 injections Anxiety or restlessness : Anecdotal reports, though causation remains unestablished It is crucial to distinguish between symptoms caused by elevated B12 levels and those arising from the underlying conditions that elevate B12

Malabsorption is the most common cause of vitamin B12 deficiency