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Am J Clin Nutr 49:283289 Roulet M, Pichard C, Rssle C, Bretenstein E, Schutz Y, Chiolero R, Frst P, Jquier E (1989) Adverse effects of high dose carnitine supplementation of total parenteral nutrition on protein and fat oxidation in the critically ill

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Additionally, while ultracentrifugation is a common method of EV isolation from biological fluids 61 , this method carries a substantial risk of sample contamination with lipoproteins and other biomolecules that are co-isolated and are fused with EVs under these conditions