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A 2025 study published in the Proceedings of the National Academy of Sciences (PNAS) highlighted that patients with post-viral dysautonomia and ME/CFS often exhibit markedly abnormal levels of plasma carnitine and free fatty acids

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Of these, 46 patients (25.1%) did not return to any medical evaluation after treatment prescription, and were therefore considered lost to follow-up and excluded from the analysis

Overuse risk: Excessive use may create an imbalance in the bodys natural L-Carnitine production