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3.3 Hydrogen sulfide and testosterone biosynthesis Low testosterone levels and hypogonadism occur in 2.15.7% of men aged 4079 years and may be a cause of male infertility (109)
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Furthermore, Nrf2 regulates the major NAD(P)H-generating enzyme, aldehyde dehydrogenase, via transcription, inducing aldehyde dehydrogenase expression in microsomes, the cytoplasm and mitochondria and generating NAD(P)H with the cofactor NAD(P) [102]
