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A chronic pro-inflammatory environment contributes to the physiopathology of actinic lentigines

Astragaloside IV enhances cisplatin chemosensitivity in human colorectal cancer via regulating NOTCH3

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ODonovan M, DeStefano AL, Jones L, Haines JL, Deleuze JF, Owen MJ, Gudnason V, Mayeux R, Escott-Price V, Psaty BM, Ramirez A, Wang LS, Ruiz A, van Duijn CM, Holmans PA, Seshadri S, Williams J, Amouyel P, Schellenberg GD, Lambert JC, Pericak-Vance MA (2019) Genetic meta-analysis of diagnosed Alzheimers disease identifies new risk loci and implicates A, tau, immunity and lipid processing

Notably, the anti-inflammatory effects are intensity-dependent, with high-intensity swimming suppressing Th1/Th17 responses more effectively than moderate exercise [300]