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Despite being naturally produced by the body, factors like age, poor diet, stress, and environmental toxins can deplete glutathione levels

As an organic solvent, chloroform enabled largescale synthesis of pharmaceuticals, accelerating drug discovery throughout the 20th century

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The low biliary copper excretion in WD was subsequently confirmed by Frommer in 1974, 59 and Gibbs and Walshe in 1980, 60 using direct measurement

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