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Pesticides, microglial NOX2, and Parkinsons disease
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Of obvious relevance to our findings, GSTP1 has recently been shown to be an IL-6 target gene (Wang et al, 2010), while inhibition of GSTP1 activity by an IL-6 or IL-6 receptor mAb correlates with increased platinum (and paclitaxel) sensitivity in renal cancer cells (Mizutani et al, 1995)
and Kamimura A
One or other of the two pathways is essential for growth of M
