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However, the application of those acids is associated with side effects including erythema, scaling and increased risk of sunburn (136-138)

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Switching to riociguat versus maintenance therapy with phosphodiesterase-5 inhibitors in patients with pulmonary arterial hypertension (REPLACE): a multicentre, open-label, randomised controlled trial
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org/ 10.1371/j ournal .pone.0066418 65
