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The standard pharmaceutical protocol uses 0.25, 0.50, 1.0, 1.7, and 2.4mg dose levels
It can trigger skin eruptions, sometimes in up to 1 in 5 (20%) treated patients
Reporting helps build the safety evidence base for investigational medicines
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Basile DP, Anderson MD, Sutton TA (2012) Pathophysiology of acute kidney injury
