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This study showed that a short course of sublingual vitamin B12, 1000 mcg daily, can significantly improve the severity of fibromyalgia as well as the anxiety score of fibromyalgia patients, the authors wrote, adding that there was no improvement in depression scores or health status scales

Recently, a structure-based screening has led to the discovery of the first NAPRT activators based on 1,2-dimethylbenzimidazole scaffolds 231 , but evidence for these compounds in boosting NAD + metabolism is still lacking

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A proper diet and adequate sunlight may help maintain vitamin levels in the long term, but supplementation is often necessary