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IGF-1R nuclear translocation is closely associated with cell proliferation in multiple breast cancer cell lines and inhibiting IGF-1R nuclear localization reduces cell proliferation and migration in both non-malignant mammary cells and breast carcinoma cells [82,83]

The availability of UV/Visible instruments equipped with 96-well plate readers as common laboratory equipment has made measuring the GSH/GSSG ratio on multiple samples a manageable procedure

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