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However, starting from day 3 of differentiation, knockdown cells exhibited a significant reduction in IP1, with a more pronounced decrease by day 4 (Fig

Detection of these low abundant peptide modifications was enabled by GSH affinity purification, tryptic digestion and capillary LC-MS

XW: Formal Analysis, Funding acquisition, Supervision, Validation, Writing review and editing

doi: 10.1194/jlr.r700019-jlr200 74 LikerB.VranecN.GrbeaD.Baar-HuskiL.MatiI.KneeviM.et al

This study suggests that pheomelanins redox-based pro-oxidant activity may contribute to sustaining a chronic oxidative stress condition through a redox-buffering mechanism