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However, any combination approach should be undertaken with medical supervision and careful monitoring of cumulative effects
Regularly evaluate patients for signs and symptoms of OIED (e.g., dysphagia, regurgitation, non-cardiac chest pain) and, if necessary, adjust opioid therapy as clinically appropriate (see CLINICAL PHARMACOLOGY)
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Schmidt, H., Grune, T., Mller, R., Siems, W
While found throughout the body, its more prominent in the liver and in fat cells
