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The observation that all four isolates were resistant to azithromycin and trimethoprim-sulfamethoxazole raises concerns, as these antibiotics are widely used for various clinical indications

The kynurenine pathway and bipolar disorder: intersection of the monoaminergic and glutamatergic systems and immune response

CagriSema is a fixed-dose combination therapy comprising two molecules administered together in a single once-weekly subcutaneous injection: semaglutide 2.4 mg, a glucagon-like peptide-1 (GLP-1) receptor agonist already approved for weight management as Wegovy, and cagrilintide 2.4 mg, a long-acting analogue of amylin, a hormone involved in appetite regulation and satiety signalling