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Symptoms unresponsive to typical methylation or neurotransmitter-based therapies

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Current AD research focuses on understanding pathology by targeting several mechanisms, such as abnormal tau protein metabolism, -amyloid, inflammatory response, and cholinergic and free radical damage, aiming to develop successful treatments that are capable of stopping or modifying the course of AD (Tamagno et al., 2021)

This transporter is especially important in brain, as discussed later

[Crossref] [Google Scholar] [PubMed] Dimopoulos N, Piperi C, Salonicioti A, Psarra V, Gazi F, Papadimitriou A, et al