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Perhaps the most striking results obtained by Kern et al

10.1002/ana.23683 Summary Keywords general anesthesia, transcriptional regulation, synaptic activity, astrocytes, neurodegenerating diseases Citation Jiwaji Z, Mrkus NM, McQueen J, Emelianova K, He X, Dando O, Chandran S and Hardingham GE (2023) General anesthesia alters CNS and astrocyte expression of activity-dependent and activity-independent genes

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The time investment of 4 additional weeks at an intermediate dose is nothing compared to the setback of severe nausea that forces you to restart at a lower dose

[DOI] [PMC free article] [PubMed] [Google Scholar] 167.Li J., Xu L., Deng X., Jiang C., Pan C., Chen L., Han Y., Dai W., Hu L., Zhang G., Cheng Z., Liu W