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Mookkan et al., 2017), transgene-free genome editing (Zhang et al., 2025b), the synthetic apomictic sorghum (Simon et al., 2025), and nanobiotechnology in sorghum (Yong et al., 2025), has greatly facilitated basic sorghum research and industrial applications in recent years

Hypoxia promotes EV secretion by impairing lysosomal homeostasis in HNSCC through negative regulation of ATP6V1A by HIF-1
Other agents, such as immunosuppressive drugs, including budesonide and azathioprine, and antibiotics, including vancomycin and metronidazole, have been tried, but their clinical effectiveness remains to be determined

Moreover, Ma et al (94) revealed that CD36 mediates fatty acid uptake via CD8+ T cells within the TME induced ferroptosis, leading to a reduction in CD8+ T cell effector function and antitumor activity
