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doi: 10.1007/s00239-024-10223-7 2 HaleniusAGerkeCHengelH

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Protection against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity by the antioxidant ascorbic acid

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Also, GB modulates the activity and expression of specific ion transporters and channels, such as H + -ATPases and metal transporter families (ZIP, NRAMP), enhancing selective uptake and sequestration of essential ions while limiting toxic metal accumulation (Hasanuzzaman et al., 2020)

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Their GATA1 mutations are frameshifts in exon 2 that result in the failure to make GATA1 protein, continued formation of GATA1-S, and thus a greatly reduced ability to regulate GATA1-targeted genes

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The benefits of cladribine for the treatment of progressive MS remains to be explored in further clinical trials (ClinicalTrials.gov NCT04695080, NCT04550455)

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