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It has also been demonstrated that the administration of NAC can significantly improve transplant-free survival in patients affected by acute liver failure not related to acetaminophen when administered during the early stages of hepatic encephalopathy

The body's natural detoxification pathways

10.1126/science.aan4665 [DOI] [PMC free article] [PubMed] [Google Scholar] 48.Herrmann A, Wllner V, Moos S, Graf J, Chen J, Kieseier B, et al

It's more like an art than a science, and you want to do the original work justice

Much of the human data is therefore older, and the compound never accumulated the kind of modern, well-controlled trials that would settle the question
