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These evidences suggest that serum androgens and AR protein levels in metabolic tissues are non-negligible factors in deciphering the mechanism behind sexual dimorphism in metabolic health, and in establishing a precise sex-based therapeutic strategy for the prevention and treatment of metabolic diseases

Based on 511 independent metabolites, the significance threshold was calculated as 0.05/511 = 0.0000978

Thymoquinone attenuates testicular and spermotoxicity following subchronic lead exposure in male rats: Possible mechanisms are involved