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Lyme disease spirochaetes possess an aggrecan-binding protease with aggrecanase activity

(2019) evaluated cardioprotective potential at two different doses of withaferin-A in wild-type and AMP-activated protein kinase domain negative (AMPK-DN) transgenic mice

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Using naturally derived polymers (e.g., modified starches, chitosan, alginate, and gelatin) and lipids not only leverages their GRAS status but also minimizes the risk of long-term persistence of nanoparticles in tissues or ecosystems (236238)
