igf-1 lr3 cancer risk Is there a role for IGF‐1 in the development of second primary cancers? Activation of insulin-like growth factor-1
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Xenofree conditions eliminate components such as fetal bovine serum (FBS) to minimize the risk of pathogen transmission to humans and ensure safety for clinical usage [83]

Iron accumulation in the mitochondria causes a lack of Fe-S clusters, which leads to increased ROS levels in the mitochondria [82], followed by ferroptosis due to lipid peroxide accumulation [83]

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The GSH/GSSG ratio is a widely accepted indicator of oxidative stress and cellular redox balance

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