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Analysis was performed using an ultra-performance liquid chromatography system (ExionLC AD, SCiex website coupled with an MS/MS system (QTRAP 6500+, SCiex website Prior to differential analysis, PCA was conducted using the PTM BioLab cloud platform ( to evaluate the variability within and between sample groups
Total protein contents were measured with the Bradford assay (Carl Roth, Karlsruhe, Germany) and adjusted with homogenization buffer to the sample with the lowest concentration (17.94 mg/ml)
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