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Mattson MP, Moehl K, Ghena N, Schmaedick M, Cheng AW

Barjaktarevic, I

39,43,46,47,48 Dosages used have ranged from 800 to 2000 mg per day in longer-term studies (212 weeks), with the highest dose seeing the largest reductions in homocysteine

Furthermore, in ovarian cancer cells, it has been observed that up-regulation of C-MYC (a gene regulating tumor proliferation) leads to a significant reduction in ROS content (104)