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Comparators, estimands, and why the design matters The most scientifically valuable design would include not just a placebo arm but a semaglutide-monotherapy arm, because the central open question is whether adding cagrilintide improves liver outcomes beyond what semaglutide already achieves

D., Knerr, P

This is not equivalent to the FDA granting approval as a therapeutic drug, and it carries no standing under UK or EU medicines law

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Feb 8, 2023: A booster shot of Moderna (the third shot, which is the same as the first two and is not the bivalent booster) was associated with spontaneously developing hives 8-13 days after the shot, that lasted six weeks or longer, according to a study in JAMA