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An improved nitrilase-mediated bioprocess for synthesis of nicotinic acid from 3-cyanopyridine with hyperinduced Nocardia globerula NHB-2

Selank was developed at the Institute of Molecular Genetics of the Russian Academy of Sciences and is based on the naturally occurring immunomodulatory peptide tuftsin (Thr-Lys-Pro-Arg, corresponding to residues 289-292 of the IgG heavy chain) with a C-terminal Pro-Gly-Pro extension derived from the proline-rich peptide family that enhances metabolic stability and CNS penetration

doi: 10.3171/jns.2006.105.5.765

Hydroxocobalamin does not have many significant drug interactions

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