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Besides, ROS trigger different phosphatases that dephosphorylate and thus inactivate kinases, thereby promoting signaling pathways
in vivo (Rempe et al., 2016)

Recent studies have found that UA may not only directly reduce oxidative stress and improve the clearance of A and -syn by inducing autophagy, but also reduce p-tau formation through Akt activation [171](Fig
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periventricular cystic lesions or intraventricular septations (occasional)
