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If you plan to resume, restart at the full dose rather than titrating back up, since the break period allows receptor resensitization

Multiple sclerosis (MS) As a chronic inflammatory demyelinating disease of the nervous system, MS is characterized by the infiltration of T cells and B cells into the central nervous system, the excessive production of inflammatory cytokines and chemokines, and the failure of the immune system to present immune responses [47]

For studies with insufficient information, the reviewers contacted the corresponding authors where possible to acquire the data

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