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While ob/ob mice show low body temperature [8], leptin administration or the artificial activation of leptin receptor in hypothalamus increases metabolic activity of rodents with body weight loss [9]

[DOI] [PubMed] [Google Scholar] 202.Alobeidat S, Athamneh T

In particular, brain organoids are revolutionizing the study of mitochondrial-based neurological diseases since they are organ-specific and model-generated from a patients cell, thereby overcoming some of the limitations of traditional animal and cell models

Vitamin B12 This component greatly influences the body
