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Transient receptor potential vanilloid-1 antagonist AMG517 playing aneuroprotective role in cerebral ischemia/reperfusion injury in mice by regulating the release of inflammatory factors
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A possible reason could be that these three enzymes are related to maintenance of adequate reduced glutathione levels, whereas GPx1 is involved in its direct consumption

[DOI] [PubMed] [Google Scholar] 116).Kiko T., Nakagawa K., Tsuduki T., Arai H., Miyazawa T

Glutathione plays a key role in protecting cells from oxidative stress and supporting the liver in detoxification processes
