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Together they function as a two-phase system: signal and scaffold first, migration and sustained remodelling second

A circadian clock gene, Rev-erb, modulates the inflammatory function of macrophages through the negative regulation of Ccl2 expression

Tippmann, E.M., Liu, W., Summerer, D., Mack, A.V
Mitochondrial and endoplasmic reticulum calcium homeostasis and cell death
As mentioned, in the brain, these genes regulate a variety of biological processes involved in the physiology of sleep and its disturbances (Sandberg et al