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3 Results 3.1 Selective reactions of the non-reduced TrxR1 to thiol-reactive reagents The structures of the thiol-reactive reagents used in this study are shown in Supplementary Table S1

Additionally, it has been linked to mood regulations and metabolic process, highlighting its broader physiological importance

Binding at this receptor triggers intracellular calcium signaling cascades in somatotroph cells of the anterior pituitary, leading to growth hormone release in a pulsatile pattern that mimics physiological secretion in animal models

however, elevated GH levels may predispose to insulin resistance or carpal tunnel-like symptoms with prolonged exposure [31]
