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CNS Neurosci Ther 15:345

Lipid Peroxidation and iron metabolism: two corner stones in the homeostasis control of ferroptosis

Several critical in vitro studies have demonstrated unique properties of ERG that are different from those of any other thiol compounds: (i) at normal physiological pH, ERG exists predominantly in the thione form rather than the thiol form 7

PC-SOD directly scavenges superoxide anions through its enzymatic activity, which differentiates it from broader antioxidant agents such as PBN and -lipoic acid, whose mechanisms are not specific to superoxide anions
