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Malondialdehyde (MDA), a byproduct of lipid peroxidation, is the most widely used biomarker of oxidative stress

GSTP1a and GSTP1b differ by an A to G substitution at codon 105 that exchanges isoleucine for valine

However, despite the cytotoxic effects of PEI, it provided the carrier with numerous characteristics, such as the proton sponge effect that aided in endosomal escape, efficient drug uptake, and intracellular drug release
