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Glutathione reductase (GR), a dimeric flavoprotein, is encoded by the GSR gene and is found in various tissues

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ATP-dependent transporters have also been reported to import glutathione into the nucleus [58]

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The E2 gene (symbol: DBT) is located on chromosome 1p21.2 and contains 14 exons that that generate three alternatively spliced mRNAs that collectively encode a 482 amino acid precursor protein (isoform 1 ) and a 3301 amino acid protein (isoform 2)