mitochondrial l-carnitine shuttle pathway The Carnitine Shuttle. The figure highlights the major components of The Biomics - Carnitine shuttle

McCulloch notes this is not something she has observed in clinical practice

doi: 10.1007/s00415-020-10057-5 18

Research in mouse models of aging has demonstrated that EGCG can modulate gutbrain communication by increasing levels of the adrenal hormone dehydroepiandrosterone (DHEA), a functional component of the HPA axis [161], and by attenuating HPA axis hyperactivity (as evidenced by reduced CRH, ACTH, and corticosterone levels) whereas simultaneously increasing the levels of SCFAs in the host [25]

However, individual supplements allow dose adjustment based on personal needs for example, adding higher-dose CoQ10 for women over 35, or myo-inositol for PCOS

The Daily Shot supports the cellular foundation that the Pre-Activity Shot then activates