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A longevity stack makes more sense when the fundamentals are covered
One factor that could explain the discordance among the prevalence data of DAO deficit in patients with disorders associated with histamine intolerance is that the parameter considered in all of them was serum DAO activity, which, a priori, would not reflect an enzymatic deficiency derived from certain intestinal pathologies
For example, both the affinity of an antibody for its antigen and the affinity with which it binds to FcR affect the stability of immune complex formation and the FcR clustering that is required to promote the signalling leading to downstream effector functions

However, these drugs are expensive and are usually associated with profound side effects
