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The above results obviously illustrated that high glucose drove mitochondrial oxidative stress-related endothelial dysfunction through the suppression of FAO

Another study reported that the inhibition of lncRNA ZFAS1 upregulated cardiac GPX4 and terminated the ferroptosis process and oxidative insult in DCM mice [95]

10.1016/j.nicl.2019.101706 Neuroimage Clin

In microglia cultures from young mice, inflammation and TGF1 prompted phagocytosis, while TGF1-induced phagocytosis was also hindered by Smad3 inhibition

We first evaluated the therapeutic potential of J10 using an A549 xenograft model, which demonstrated significant tumor growth inhibition when administered at 10 mg/kg every other day (Fig