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Although rupture of the plasma membrane represents the terminal event of ferroptotic death, emerging evidence indicates that ferroptotic signaling is initiated at intracellular membrane compartments, including the ER, Golgi-associated vesicles, and lysosomes 107-110

P53 phosphorylation at Ser15 enhances the affinity of both FOXO4 and FOXO4-DRI for p53 TAD2 explaining the preferential engagement of FOXO4-DRI with the hyperphosphorylated p53 characteristic of senescent cells
10.1111/mmi.13251 [DOI] [PubMed] [Google Scholar] Salman-Dilgimen A, Hardy PO, Dresser AR, and Chaconas G (2011)

Neutrophils Neutrophils are very powerful white blood cells that specialize in killing bacteria and fungi

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