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Markers of Circadian Phase The minimum of the core body temperature (CBTmin) and the dim light melatonin onset (DLMO) are two useful markers of the position of an individuals circadian rhythms with respect to the external environment (i.e., time of day) (Box 262)

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Dihexa was administered orally via gavage at doses of 1.25 mg/kg or 2.0 mg/kg, 25 minutes before behavioral testing

The drug was developed in the 1940s by Albert Hofmann [138], and thus, is one of the oldest nootropic drugs still in use

Giustina A, Scalvini T, Tassi C, Desenzani P, Poiesi C, Wehrenberg WB, Rogol AD, Veldhuis JD