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10.3390/ijms14011455 11 ChomczynskiP.MackeyK
It was shown in vitro using ZF cell lines that constant ACTH treatment led to larger increase in pCREB and steroidogenic gene transcription at the start of treatment but the cells became unresponsive to the stimuli over time (158)

PMID 20019124

In fatty liver disease, where metabolic stress is elevated, maintaining adequate glutathione levels theoretically supports these critical detoxification pathways

J Thorac Oncol 19(9):1326-1338, 2024