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The complexes induce endoplasmic reticulum (ER) stress by inhibiting ubiquitin-proteasome system (UPS) activity, leading to polyubiquitinated protein accumulation and activation of the unfolded protein response (UPR)

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Ferroptosis as a P53-Mediated Activity During Tumour Suppression

When a substrate interacts with two GDH trimers, a projecting domain that resembles an antenna connects the subunits (Nassar et al., 2019)
10.1080/10408444.2021.1903386 81 YuL