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When a drug such as atorvastatin (the Ligand) enters the cell, it can bind to a nuclear receptor such as the pregnane X receptor (PXR)
[PubMed] [Google Scholar] 79.Ilic S., Drmic D., Franjic S., Kolenc D., Coric M., Brcic L., Klicek R., Radic B., Sever M., Djuzel V., et al
During injury states, this balance shifts to strongly elevate NOS2 expression specifically in healing contexts
For most other minerals, the effect is minimal
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