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Nevertheless, microbiome and immunomics studies remain sensitive to sampling location, contamination control, sequencing depth, and inter-cohort variation, which complicates reproducibility and interpretation

Proc Natl Acad Sci U S A 75(4):1938-42, 1978
Bcl-x(L) retrotranslocates bax from the mitochondria into the cytosol

They may be obvious to the naked eye or can be found incidentally by imaging studies of the neck, such as a sonogram of the carotid arteries or a CT or MR of the spine

Using proteomics, a recent study identified that this mutation promoted ATP7B interaction with heat shock protein 70 (HSP70), accelerating its degradation in the ER