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But the weight gain is not a direct result of the deficiency but rather an indirect result

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Elevated oxidative stress fosters the proliferation and hypertrophy of vascular smooth muscle cells, as well as collagen deposition, culminating in vascular medial thickening and constriction

This accounts for the people in the research that found 98% of their injected vitamin B12 in their urine 48 hours after it was administered

This means results may plateau if caloric intake drifts upward, as AOD-9604 enhances fat oxidation but does not override positive energy balance